Methylenetetrahydrofolate or MTHFR, is a fairly common genetic mutation that can have significant consequences. This gene is responsible for Methylation in the body. Methylation is a biochemical process that occurs in every cell in the body. Hormones, enzymes and genes are all affected by methylation. Methylation can turn genes off and on, help enzymes work and help with detoxification.
MTHFR is specifically involved with the methylation of folate and homocysysteine. Testing for MTHFR Genotype can provide information concerning many important health factors.
There are many medical conditions associated with this gene: Parkinson’s, Alzheimer’s, Autism, Atherosclerosis, Depression, Anxiety, ADHD symptoms, Insomnia, Cardiovascular Disease, Infertility and Recurrent Miscarriages, Chronic Viral Infections, Chronic Pain, Cancer, Thyroid Dysfunction are just a few of these conditions.
No one will have all of these disorders but if there tends to be several of these running through the family, there is a chance the MTHFR gene is present.
Every woman of childbearing age, who plans to become pregnant, should be tested. It could save a lot of grief. Folic Acid is recommended for women who are pregnant or are planning to be so. If the MTHFR gene is present, metabolism of the folic acid can be impaired. If the gene is present, the methylated forms of Folate and Vitamin B12 must be used.
Many nutritional companies are aware of this and are making their supplements with the methylated forms. However, if someone does not have the gene mutation, the methylated form is not necessary and could be harmful.
A woman with severe arthritis was almost disabled until we discovered she had this gene mutation. With the proper nutritional support, she is like a different person. She feels much better, has much less pain and can move without the help of a cane or walker.
Foods that are high in Folate include: Almonds, artichokes, asparagus, avocado, banana, beans (black, garbanzo, green beans, lima, navy, kidney, pinto), beets, broccoli, Brussels sprouts, cantaloupe, carrots, cauliflower, celery, corn, dark leafy greens (collard greens, mustard greens, romaine lettuce, spinach and turnip greens), flax seeds, grapefruit, grapes, green onions, lentils, okra, orange juice and oranges, papaya, peanuts, peas (green, chickpeas, split peas), potatoes, raspberries, red peppers (sweet), squash, strawberries, sunflower seeds and yeast.
Environmental toxins such as mercury, aluminum and arsenic as ell as medications such as antacids, can have a negative impact on the person with this gene mutation. Also depletion of important nutritional cofactors such as Magnesium, Vitamin B6 and Zinc can create an adverse environment.
Many doctors are unaware of the importance of this gene but testing for the MTHFR Genotype can provide information concerning many important health factors.